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Non-selective melanocortin receptor agonist
Melanotan II is a synthetic peptide catalogued as a non-selective melanocortin receptor agonist, molecular formula C50H69N15O9 at approximately 1024.2 g/mol, supplied as a lyophilized reference material in a 10mg vial with a published certificate of analysis.
Melanotan II is a synthetic peptide supplied as a dry laboratory reference material. Its molecular formula is C50H69N15O9 and its molecular weight approximately 1024.2 g/mol, the two figures printed on the certificate published for the 10mg size, which files the material against PubChem CID 92432. Those two figures reconcile exactly against standard atomic weights: carbon 600.550 plus hydrogen 69.552 plus nitrogen 210.105 plus oxygen 143.991 sums to 1024.198 g/mol, which rounds to the certified 1024.2. Chemical databases file the compound under InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N, an identifier the certificate does not print; it is carried here from the PubChem record for CID 92432 and is stated as such. A rounded molecular weight is a weak identity check on its own, and melanocortin analogs are among the species third-party listings most often file against each other. The molecular formula, the PubChem CID and the InChIKey are the fields that pin the species down, and they are the ones to read when a catalog listing and a certificate disagree. Supplied as a white lyophilized powder in a sealed 10mg vial; identity and purity characterized by ultra-high-performance liquid chromatography with mass spectrometry against a purity specification of 98 percent minimum. It is not supplied as a solution, a spray, a cream or any other prepared formulation. v e r t catalogs the material as a non-selective melanocortin receptor agonist, and it has been investigated in laboratory research into melanocortin-receptor signaling pathways.
>99% UPLC purity; identity confirmed by mass spectrometry. A Certificate of Analysis is published for each size, reporting that lot's identity and purity result. See our quality & COA page.
Supplied as a lyophilized reference material. Lyophilized reference materials are stored desiccated at 68°F (20°C), away from light and moisture. We do not provide reconstitution, preparation, or usage instructions of any kind.
Melanotan II is a synthetic peptide supplied as a dry laboratory reference material. v e r t catalogs it as a non-selective melanocortin receptor agonist, which is a class descriptor for where the compound sits in the literature rather than a statement about what it does anywhere, and it has been investigated in laboratory research into melanocortin-receptor signaling pathways. On identity the fields that matter are the molecular formula C50H69N15O9, a molecular weight of approximately 1024.2 g/mol and PubChem CID 92432, all three printed on the certificate published for the 10mg size, together with InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N, which the certificate does not print. It is supplied as a lyophilized reference material, not as a formulation.
They do, and the arithmetic is worth showing, because peptide listings routinely print a mass that belongs to a neighboring species. Take the certified formula C50H69N15O9 and sum it from standard atomic weights: carbon contributes 50 times 12.011, or 600.550; hydrogen 69 times 1.008, or 69.552; nitrogen 15 times 14.007, or 210.105; oxygen 9 times 15.999, or 143.991. The total is 1024.198 g/mol, which rounds to the certified 1024.2. Read that for what it is. It is an internal consistency check showing that the two figures on the certificate describe the same species, and nothing more than that; it is not an independent confirmation of what is in the vial. Identity itself is established by mass spectrometry, and the species is pinned publicly by PubChem CID 92432.
They are different kinds of identifier and they fail in different ways. PubChem CID 92432 is a record number: it points at one entry in one public database, it was assigned rather than calculated, and it is the quickest way to check that a listing and a certificate mean the same compound. The InChIKey is computed from the structure itself. JDKLPDJLXHXHNV-MFVUMRCOSA-N is a fixed-length hash in three parts: the first block, JDKLPDJLXHXHNV, encodes the molecular skeleton and its connectivity; the middle block encodes the remaining layers, stereochemistry among them, and carries flags for the InChI version and standard form; the single trailing character records protonation state. Two compounds differing only in stereochemistry therefore share a first block and diverge in the middle one, which is worth knowing before treating a partial key match as confirmation of identity. Our certificate prints no InChIKey. The one on this page is carried from the PubChem record for CID 92432, and is labelled that way in the specification table rather than presented as a certified figure.
A certificate is published for the 10mg size at /coa/melanotan-ii-10mg.pdf, carrying the date its analysis was conducted. The method printed on the document is qualitative and quantitative chemical analysis by ultra-high-performance liquid chromatography with mass spectrometry, against a purity specification of 98 percent minimum. Its second page carries the analytical data plates under the headings Ultra High Performance Liquid Chromatography and Mass Spectrometry. The two headline items answer different questions. Mass spectrometry establishes identity, matching an observed molecular ion against the expected mass for C50H69N15O9. Chromatographic purity is an area-percent figure, the integrated area of the main peak divided by the total integrated peak area, which is a relative measure of chromatographically resolved organic impurities. Area-percent is not an assay of absolute content. It does not account for water, residual solvent, counter-ion mass, or any species that neither retains on the column nor absorbs at the detection wavelength. The document reports identity, appearance, quantity, purity against the stated specification, molecular formula, molecular weight and the plates above. It does not report water or moisture content, residual solvent, peptide content by nitrogen determination, endotoxin or bioburden. Anything absent from the certificate is not certified by it. This page states the specification and not the figures particular to any one lot: lot figures turn over every time the lot does, and the document itself is where they belong.
Melanotan II ships in one size, 10mg, as a sealed vial of dry material, and the certificate records its appearance as White Lyophilized Powder. It is not supplied as a solution, a spray, a cream or any other prepared formulation, and every figure on this page describes the dry material as supplied. Storage is desiccated at 68°F (20°C), away from light and moisture.
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